Is Juvederm better than Restylane?

I’ve been thinking about adding some volume to my face… being 46 and losing weight didn’t help my condition. Everyone I’ve talked to seems to have a different opinion on which is better: Juverderm or Restylane. So my question is the following: Are either of these two fillers longer lasting or have more natural looking results than the other? I understand that Restylane is more difficult to work with because it needs to be molded once injected, while Juvederm diffuses in the tissues. Is this true?


F, 49, Connecticut

Either dermal filler is good and, administered properly, should give you the desired look. If you research Juvederm vs. Restylane online, you'll probably see a split among dermatologists or board-certified plastic surgeons on which they prefer using.

Both Juvederm, which is manufactured by Allergan, and Restylane, which is manufactured by Galderma, consist of hyaluronic acid. They contain no human or animal DNA and have some of the highest safety profiles in the "filler" category. Both are FDA approved for use in nasolabial folds -- referred to as smile or laugh lines -- and are sometimes used off-label in other areas.

Some doctors have recently started to switch to Juvederm, as doctors have indicated it tends to be smoother upon injection and provides a little extra volume than Restylane. However, either will do the trick.

In the end, it's the experience and technique used by the injector that is the most important ingredient in this equation. So, for the best results to attack those fine lines, make sure you look around to find qualified people who have a successful track record performing this procedure.

I was a Restylane user but switched to Juvederm years ago. Why? I found that Juvederm is a smoother gel than Restylane. If you squeeze a little of each on a glass slide, you will see the difference. I think this makes Juvederm easier to inject smoothly. Because there are some differences in the cross-linking of the molecules in the two, I think it is possible that Juvederm lasts a little longer. Is all of this significant? Probably not really. Every injector will have preferences. I think the product, hyaluronic acid, is a terrific material for its many applications. I think it has no peer in the lips. Unfortunately, it is not good when a lot of volume is needed. If your issue is really volume loss, you might wish to consider fat grafting. The extra expense will be more than offset by the fact that this will provide as much volume as you are likely to need, is totally "natural", and is likely to be permanent. 

Juvederm and Restylane are both hyaluronic acid fillers. There is no clear answer to your questions because each filler has it's place. The best filler for your face depends on your areas of concern and the areas of the face that need to be injected. Both Juvederm and Restylane can be injected into the lips and the nasolabial folds. However, Juvederm may not be the best product to inject into the tear trough ( groove under the eyes). I recommend that you have a consultation with an injector and allow that expert to make recommendations regarding which filler is the best for you. 

Linda Kelley has 2 Fillers before & afters:

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There are several skincare options for people who are not at the point of visiting a cosmetic surgeon and committing to facelift surgery. Injectable dermal fillers such as Juvederm and Restylane, as well as a handful of others, are FDA-approved. They're all good products, but Juvederm and Restylane are the most popular.

Filler treatments like these are used primarily for skin rejuvenation and to fill the under-eye area, frown lines, etc. on your face -- lines that run from your nose to your mouth and the crease of your smile down toward your chin. They're also popular for lip augmentation that gives the appearance of fuller lips.

No filler is permanent. The effects can last anywhere between 6 and 12 months. In some instances, neurotoxins (like Botox) and fillers are used in tandem to enhance overall appearance.

There is really no product that is better or worse than the other, although there may be a slight difference in the price of Juvederm and Restylane treatments (you're charged by the syringe). The provider you ultimately choose will likely favor one filler over the other. Ask them why. And, be sure to look around for someone that has a lot of experience in injectables. You want someone with solid credentials in these types of cosmetic procedures.

As for post-procedure -- there is no real downtime associated with either treatment, although you may encounter some slight bruising and swelling directly on the injection sight. You can use ice immediately following to reduce this. The results from the injections are almost immediate, but make take a day or so for the filler to settle.

Dr. Landon Pryor has 5 Filler to lip lines before & afters:

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Hello, and thank you for your question! Both Juvederm and Restylane are the same exact product, hyaluronic acid based fillers. A large part of my practice is using a procedure that I call Aesthetic Facial Balancing. What this means is evaluating a patients face and bringing the features into harmony by making adjustments with either hyaluronic acid such as Restylane or fat. The most important component of a fillers treatment is the practitioner administering it. I take filler and balance all features in your face from top to bottom to make them work together to 'unlock' your beauty. This procedure is not just a filler intervention augmenting the cheeks and lips, but as in overall, non surgical way to shape the face in a different way to create natural appearing results. The amount of syringes depends on the patient, and it would be best for an in-office consult to assess. I hope this helps! Wishing you fantastic results, Dr. Rian A. Maercks M.D.

Rian Maercks has 1 Hyaluronic Acid Filler before & after:

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In my opinion, they are so similar that I would use whichever one your PS suggests- they are going to be most familiar with a product family (restylane, restylane lyft, restylane silk from Galderma) or (Juvederm, Juvederm Voluma, Juvederm Volbella from Allergan). In addition, they may offer better pricing or points program promotions from one company or the other.

In my opinion, volume enhancement in the mid-face using a filler product is best served by Restylane Lyft, or a collagen stimulator like Sculptra. If you are concerned with longer lasting product, look into Sculptra.  Only specific providers are trained in this product- however, because it is not a filler but a collagen stimulator it takes multiple injections over a several month period. 

Jack Peterson has 1 Fillers before & after:

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I have used both products since they were made available in the United States. I would not say that one is better than the other or that one is more difficult to work with for the experience injector.  Each is made of the same chemical compound, hyaluronic acid.  Each has a role and when each is used for its intended purpose by n experience injector each provides a good result.  Given your description of your issues and your weight loss you should consider Voluma, which is designed to provide volume specifically.  Best of luck.

Hi Conniie99,

The differences between the two products are subtle at best.  Both are hyaluronic acid, just with a different manufacturing process.  Your doctor will decide which filler product is best for you, and it varies depending on their experience, preferences, pricing, and which application they are using it for on your face.  For instance I love Juvederm for lips, but would never use it under the eyes.

Yoash R. Enzer, MD, FACS

Providence, RI


   Good question, I don't agree that one of these products is better than the other. They are slightly in their viscosity but both are hyaluronic acid fillers that is a naturally occurring substance in the skin and very safe. They are excellent options to restore volume in certain areas of your face. Good Luck!

Every injector will have different opinions of different fillers but essentially Juvederm and Restylane are the same thing. They are both hyaluronic acid. Each brand has different types (sub types) of filler and that can affect their use, their longevity, and the amount of swelling and change noted more than the difference in brands.

For volume I prefer other fillers or volume "stimulators". Juvederm is my favorite for moderate folds and lines. Restylane I use in what is nicknamed the "tear trough" . Different fillers have different properties,  Fillers  for volume (cheeks etc.) are Voluma (a Juvederm product), Restylane Lyft, and Sculptra that is not a filler but a collagen stimulator. Make sure you get several options and detailed benefits and expectations with each.

Manuel Pena has 1 Filler to lip lines before & after:

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